For Immediate Release

7/18/06

A Protein In Blood Can Signal The Spread Of Cancer Cells

Goshen, Ind. - A specific protein in the blood may signal the spread of cancer cells. Identifying this substance in the blood of a cancer patient's body can provide physicians with information that might assist them in further individualizing treatment.

A study of the protein tNOX messenger RNA was recently performed in partnership by researchers from the Center for Cancer Care at Goshen Health System and Purdue University. In the study, the blood from 32 cancer patients with breast, lung and ovarian cancers, as well as 22 healthy volunteers was tested for the protein with the latest molecular technology. Each person with cancer was shown to have the protein substance, while none of the volunteers were positive for the protein.

"The identified protein may act as a marker pointing to the spread of cancer cells. Further study is needed, but it is hoped that the recognition of this protein will provide valuable information to properly recognizing the extent of cancer within the body," explained Dr. Kenneth Pennington, Board Certified Medical Oncologist with the Center for Cancer Care at Goshen Health System, Goshen, Indiana.

D. James Morre, Ph.D., Professor of Medicinal Chemistry, Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana noted, "this protein appears to be needed for the cancer cells to maintain their unregulated growth. Knowing more about this substance will surely lead to other discoveries regarding the disease, as well."

The mission of the Department of Medicinal Chemistry and Molecular Pharmacology of Purdue University is to serve the citizens of Indiana, the United States and the world through discovery, learning and engagement that integrates the basic chemical and biological sciences for the improvement of human health. Visit their website at www.mcmp.purdue.edu.

The Center for Cancer Care at Goshen Health System is a leader in innovative cancer treatment. Among the first to adopt a comprehensive approach to treatment, the Center offers holistic programs for strengthening minds as well as bodies, and places a premium on family involvement and spiritual needs. Patients are encouraged to play a decision-making role in treatment selection. For cancer treatment information call 1-866-496-HOPE.

Goshen Health System is a not-for-profit provider of health care that includes Goshen General Hospital, The Center for Cancer Care, Park Home Medical Equipment, PrimeCare Physician Network, Team:Bariatrics, The Retreat Women's Health Center and Indiana Lakes Managed Care Organization. The health system is an affiliate partner of Clarian Health, which includes Indiana University Hospital, Methodist Hospital of Indianapolis and Riley Hospital for Children. For more information about Goshen Health System, contact visitwww.goshenhealth.com.